Glutarate

Glutarate

SCHEMBL4060585

C1=CCCC1.O=C(O)CCCC(=O)O

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.58
LMNA P02545 4/20 0.50
TSHR P16473 3/20 0.48
NFKB1 P19838 2/20 0.48
PMP22 Q01453 1/20 0.48
BBOX1 O75936 2/20 0.45
CAMK2A Q9UQM7 1/20 0.43
CYP1A2 P05177 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
HDAC3 O15379 1/20 0.42
GABBR2 O75899 1/20 0.42
THRB P10828 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRR1 P24046 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRR2 P28476 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL4049809 0.90 LMNA (0.58) SLC22A6LMNATSHRNFKB1PMP22
Octanedioate SCHEMBL4055387 0.85 TSHR (0.57) SLC22A6LMNATSHRNFKB1PMP22
Octanedioate SCHEMBL4055395 0.85 TSHR (0.57) SLC22A6LMNATSHRNFKB1PMP22
Succinic Acid SCHEMBL29181188 0.83 LMNA (0.53) SLC22A6LMNATSHRNFKB1PMP22
Dodecanoate SCHEMBL27802307 0.83 GPR84 (0.68) SLC22A6LMNATSHRCYP1A2BLM
Glutarate SCHEMBL3859608 0.80 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL8744382 0.80 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL27580861 0.80 SLC22A6 (0.79) SLC22A6LMNATSHRNFKB1PMP22
Cyclopentene SCHEMBL4818209 0.76
Glutarate SCHEMBL27824860 0.76 SLC22A6 (0.85) SLC22A6LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108295889-A A kind of oxidation of cyclopentene synthesizing glutaric acid mesoporous silicon oxide supported tungsten oxide catalysts and preparation method thereof 青岛科技大学 2018-07-20 CN disclosed
WO-2009109857-A1 METHOD FOR PRODUCING CARBOXYLIC ACIDS BY OXIDATIVE CLEAVAGE OF UNSATURATED COMPOUNDS UNIVERSITEIT LEIDEN (NL) 2009-09-11 WO disclosed