SCHEMBL4060593

SCHEMBL4060593

CCC(c1cc(Cl)c(O)cc1O)c1cc(Cl)c(O)cc1O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
TSHR P16473 4/20 0.41
HSD17B10 Q99714 3/20 0.41
HPGD P15428 1/20 0.41
PGK1 P00558 1/20 0.37
BCHE P06276 2/20 0.35
TYR P14679 2/20 0.35
ACHE P22303 2/20 0.35
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
HSP90AA1 P07900 4/20 0.34
HSP90AB1 P08238 2/20 0.33
CA2 P00918 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HKDC1 Q2TB90 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8350553 0.88 TSHR (0.46) LMNATSHRHSD17B10HPGDPGK1
SCHEMBL4062096 0.84 ALOX15 (0.44) LMNATSHRHSD17B10HPGDPGK1
SCHEMBL21686455 0.76 LMNA (0.69) LMNATSHRHSD17B10HPGDALOX15
SCHEMBL4055501 0.76 LMNA (0.52) LMNATSHRHSD17B10HPGDPGK1
SCHEMBL23214644 0.71 LMNA (0.47) LMNATSHRHSD17B10HPGDACHE
SCHEMBL15944087 0.71 LMNA (0.52) LMNATSHRHSD17B10HPGDPGK1
SCHEMBL4064362 0.70 ATM (0.41) LMNATSHRHSP90AA1CA2TDP1
SCHEMBL8764418 0.70 GPR84 (0.40) LMNA
SCHEMBL1575424 0.69 ESR2 (0.47) LMNATSHRHSD17B10HPGDBCHE
SCHEMBL23214636 0.69 LMNA (0.41) LMNATSHRHSD17B10HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM LMNA 202/4885TSHR 4402/4885HSD17B10 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.