Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114440 | 0.89 | MAPT (0.58) | MAPTALDH1A1TDP1MAOBMEN1 | |
| SCHEMBL5248983 | 0.82 | NFE2L2 (0.51) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5442818 | 0.82 | MAPT (0.66) | MAPTALDH1A1TDP1MAOBMEN1 | |
| SCHEMBL1578983 | 0.82 | MAPT (0.66) | MAPTALDH1A1TDP1MAOBMEN1 | |
| SCHEMBL29594574 | 0.82 | MAPT (0.66) | MAPTALDH1A1TDP1MAOBMEN1 | |
| SCHEMBL1578978 | 0.82 | MAPT (0.66) | MAPTALDH1A1TDP1MAOBMEN1 | |
| SCHEMBL9978289 | 0.80 | MAPT (0.69) | MAPTALDH1A1MAOBMEN1KMT2A | |
| SCHEMBL14935499 | 0.80 | MAPT (0.69) | MAPTALDH1A1MAOBMEN1KMT2A | |
| SCHEMBL11049170 | 0.80 | MAPT (0.69) | MAPTALDH1A1MAOBMEN1KMT2A | |
| 2-Nitrobenzaldehyde SCHEMBL11730170 | 0.80 | ERN1 (0.58) | MAPTALDH1A1TDP1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 851 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | claimed |
| EP-2727915-A1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | Concert Pharmaceuticals Inc. (US) | 2014-05-07 | — | — | EP | claimed |
| EP-2177522-B1 | NOVEL CARBAPENEM DERIVATIVES | XUANZHU PHARMA CO LTD (CN) | 2013-09-04 | — | — | EP | claimed |
| US-7244411-B2 | Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-07-17 | — | — | US | claimed |
| EP-1795896-A2 | Method for the identification and relative quantification of proteins based on the selective isolation of RRNK peptides for the simplification of complex mixtures of proteins | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) (CU) | 2007-06-13 | — | — | EP | claimed |
| US-20070128729-A1 | Method for the identification and relative quantification of proteins based on the selective isolation of RRnK peptides for the simplification of complex mixtures of proteins | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-06-07 | — | — | US | claimed |
| EP-1785729-A2 | A method for the selective isolation of multiply-charged peptides applicable in the quantitative proteomics | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) (CU) | 2007-05-16 | — | — | EP | claimed |
| US-20070099304-A1 | Method for the selective isolation of multiply-charged peptides applicable in the quantitative proteomics | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-05-03 | — | — | US | claimed |
| EP-1589341-A2 | Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) (CU) | 2005-10-26 | — | — | EP | claimed |
| US-20050176085-A1 | Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2005-08-11 | — | — | US | claimed |
| US-5837873-A | PROTECTED OXYDIAMINES | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | claimed |
| US-4771134-A | Ring-opening process for preparing azetidinone intermediates | FARMITALIA CARLO ERBA S.P.A. (IT) | 1988-09-13 | — | — | US | claimed |
| US-4713450-A | 2-thiacephems and (5R) penems derivatives | FARMITALIA CARLO ERBA S.P.A. (IT) | 1987-12-15 | — | — | US | claimed |
| US-4596759-A | Base layer, solid positive working resist consisting of two layers with different solubilities, photosensitive component containing aromatic o-nitrocarbinol esters | BASF AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | claimed |
| US-4585874-A | Process for preparing penem derivatives | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-04-29 | — | — | US | claimed |
| US-12024580-B2 | Resin composition suitable for printing and printing methods | Montanuniversität Leoben (AT) | 2024-07-02 | — | — | US | disclosed |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-0122154-A2 | Improvements in or relating to benzothienylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |
| EP-0046083-A2 | Photolabile blocked surfactants and compositions containing the same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | ADH5, ADH1A, ADH7 | MAPT 4170/4885ALDH1A1 69/4885TDP1 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.