Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839092 | 0.95 | MAPK1 (0.50) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL1646651 | 0.83 | TDP1 (0.52) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL3530264 | 0.83 | TDP1 (0.52) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL7912766 | 0.83 | TDP1 (0.52) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL2812395 | 0.81 | TDP1 (0.53) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL10879986 | 0.81 | TDP1 (0.53) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL10965695 | 0.81 | ALDH1A1 (0.63) | HSD11B1MAPK1ALDH1A1POLBCES1 | |
| SCHEMBL1023276 | 0.80 | HSD11B1 (0.60) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL12208260 | 0.80 | HSD11B1 (0.56) | HSD11B1TDP1MAPK1ALDH1A1POLB | |
| SCHEMBL1648359 | 0.80 | TDP1 (0.48) | HSD11B1TDP1MAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291417-B1 | NOVEL (R)-2-HYDROXY-3-PHENYLPROPIONATE (D-PHENYLLACTATE) DEHYDROGENASE AND GENE ENCODING THE SAME | MEIJI SEIKA KAISHA (JP) | 2007-02-21 | — | — | EP | claimed |
| EP-3790876-B1 | ENDOPARASITIC DEPSIPEPTIDES | ZOETIS SERVICES LLC (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-112384511-B | Endoparasite depsipeptides | 硕腾服务有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| US-20230241243-A1 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20220323540-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-10-13 | — | — | US | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| EP-0903347-A1 | NOVEL CYCLIC DEPSIPEPTIDE PF1022 DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1999-03-24 | — | — | EP | disclosed |
| CN-1208439-A | Process for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms | BAYER AG (DE) | 1999-02-17 | — | — | CN | disclosed |
| US-5847121-A | Production of nitro-benzyl-dota via direct peptide cyclization | NEORX CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0816316-A1 | PROCESS FOR PRODUCING 1,2-ETHANEDIOL DERIVATIVES | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0736035-A1 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5541287-A | DIAGNOSIS USING CYCLIC TRIPEPTIDES WITH NITROBENZYL 1,4,7,10-TETRAAZACYCLODODECANE-N,N*,N**,N***TETRAACETIC ACID BIOTIN CONJUGATE FORMED BY ALKYLATION AND MULTISTAGE PROCESS | NEORX CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1995015335-A2 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1995-06-08 | — | — | WO | disclosed |
| EP-0040932-B1 | AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-03 | — | — | EP | disclosed |
| US-4386080-A | 3,4-DISUBSTITUTED-N-ACYLANILINES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-31 | — | — | US | disclosed |
| EP-0040932-A1 | Amide derivatives, process for their manufacture and pharmaceutical or veterinary compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | HSD11B1 1836/4885TDP1 1937/4885MAPK1 2920/4885 |
| US-20220211802-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | HSD11B1 1836/4885TDP1 1937/4885MAPK1 2920/4885 |
| US-20230241243-A1 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | NDC1, KIFC1, SDCBP | HSD11B1 4405/4885TDP1 1064/4885MAPK1 4018/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | HSD11B1 1485/4885TDP1 3426/4885MAPK1 2900/4885 |
| US-20220323540-A1 | Endoparasitic Depsipeptides | VIP, PREP, VIPR1 | HSD11B1 1485/4885TDP1 3426/4885MAPK1 2900/4885 |
| US-11331369-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | HSD11B1 1836/4885TDP1 1937/4885MAPK1 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.