Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL27638222 | 0.97 | ALDH1A1 (0.35) | ALDH1A1CYP2A6CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27473045 | 0.96 | CA12 (0.33) | ALDH1A1CYP2A6CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8674061 | 0.87 | ALDH1A1 (0.38) | ALDH1A1CYP2A6HPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4910747 | 0.87 | ALDH1A1 (0.30) | ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27480139 | 0.84 | CES1 (0.37) | ALDH1A1CYP2A6HPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3092658 | 0.84 | ALDH1A1 (0.39) | ALDH1A1CYP2A6KDM4EHPGDMAPT | |
| Hydrochloric Acid SCHEMBL27476745 | 0.83 | HTR7 (0.32) | CASP3SENP8SENP7SENP6HTR7 | |
| Hydrochloric Acid SCHEMBL27298127 | 0.82 | HSD11B1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4068167 | 0.82 | ALDH1A1 (0.35) | ALDH1A1CYP2A6CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL4094244 | 0.82 | ALDH1A1 (0.35) | ALDH1A1CYP2A6CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101538389-B | Polypropylene resin composition | NOVOLEN TECH HOLDINGS CV | 2013-04-03 | — | — | CN | claimed |
| CN-101291960-B | Impact copolymer of propylene prepared in single reactor | TOTAL PETROCHEMICALS RES FELUY | 2012-11-07 | — | — | CN | claimed |
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | claimed |
| CN-101538389-A | Polypropylene resin composition | NOVOLEN TECH HOLDINGS CV | 2009-09-23 | — | — | CN | claimed |
| CN-101225135-A | Olefin copolymer and preparation method thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2008-07-23 | — | — | CN | claimed |
| CN-1946748-A | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-04-11 | — | — | CN | claimed |
| CN-1798803-A | Polypropylene resin composition | NOVOLEN TECH HOLDINGS CV (NL) | 2006-07-05 | — | — | CN | claimed |
| CN-1769314-A | Copolymer of olefin and omega-tolyl-alpha-olefin and its preparation method | CHINA PETROLEUM & CHEMICAL (CN) | 2006-05-10 | — | — | CN | claimed |
| CN-117946309-A | Polymerization method of polybutene-1 and preparation method of polybutene-1 resin | 中国石油化工股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117402275-A | Metallocene catalyst and preparation method thereof | 中国石油天然气股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-111217950-B | Poly-alpha-olefin having uniform structure and method for preparing same | DL化学株式会社 | 2022-09-20 | — | — | CN | disclosed |
| CN-111217950-A | Poly α olefin with uniform structure and preparation method thereof | 大林产业株式会社 | 2020-06-02 | — | — | CN | disclosed |
| CN-106459246-B | Process for producing olefin polymer, catalyst for olefin polymerization, and olefin polymer | 出光兴产株式会社 | 2020-04-10 | — | — | CN | disclosed |
| CN-101538389-B | Polypropylene resin composition | NOVOLEN TECH HOLDINGS CV | 2013-04-03 | — | — | CN | disclosed |
| CN-1217685-A | VULCANIZED MOLDING HAVING SURFACE DECORATIVE LAYER, PAINTED THERMOPLASTIC RESIN COMPOSITION AND PAINTED ELASTOMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 1999-05-26 | — | — | CN | disclosed |
| CN-1216055-A | RUBBER COMPOSITIONS FOR TIRES | MITSUI CHEMICALS INC (JP) | 1999-05-05 | — | — | CN | disclosed |
| CN-1216053-A | SHRINKABLE FILM MADE FROM OLEFINE COPOLYMER | MITSUI CHEMICALS INC (JP) | 1999-05-05 | — | — | CN | disclosed |
| CN-1209827-A | 'alpha'-olefin/aromatic vinyl copolymer composition and products thereof | MITSUI CHEMICALS INC (JP) | 1999-03-03 | — | — | CN | disclosed |
| US-5770753-A | ADDITION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |
| CN-1137527-A | Metallocene compound and its use as catalyst component | HOECHST AG (DE) | 1996-12-11 | — | — | CN | disclosed |