Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360256 | 0.73 | HTR2A (0.62) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL4053587 | 0.73 | PPARG (0.47) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL6770793 | 0.72 | KDM4E (0.64) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL4053397 | 0.72 | MCL1 (0.50) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL4064985 | 0.72 | PPARA (0.51) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL4061859 | 0.71 | MCL1 (0.42) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL6616076 | 0.71 | KDM4E (0.51) | KDM4EPPARGPPARDPPARA | |
| SCHEMBL4060883 | 0.70 | MCL1 (0.41) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL6983069 | 0.69 | GAA (0.56) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL4055592 | 0.69 | PPARA (0.54) | GAAALDH1A1KDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689389-A4 | INDOLE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-06-17 | — | — | EP | disclosed |
| EP-1689389-A2 | INDOLE COMPOUNDS | National Health Research Institutes (TW) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056522-A2 | INDOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-23 | — | — | WO | disclosed |