Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844651 | 0.89 | LMNA (0.48) | OPRM1L3MBTL1PFKFB3NPSR1NPBWR1 | |
| SCHEMBL1750412 | 0.85 | MAPT (0.50) | HTTOPRM1L3MBTL1KDM4EPFKFB3 | |
| SCHEMBL1751055 | 0.83 | ESR1 (0.42) | HTTOPRM1L3MBTL1KDM4EPFKFB3 | |
| SCHEMBL1749799 | 0.82 | RAB9A (0.54) | HTTL3MBTL1RAB9AMAPTNPSR1 | |
| SCHEMBL5844822 | 0.79 | RAB9A (0.35) | HTTL3MBTL1PFKFB3RAB9AMAPT | |
| SCHEMBL4060284 | 0.77 | RAB9A (0.47) | HTTL3MBTL1PFKFB3RAB9AMAPT | |
| SCHEMBL11724179 | 0.77 | HTT (0.54) | HTTOPRM1L3MBTL1KDM4ERAB9A | |
| SCHEMBL5843172 | 0.75 | PKM (0.41) | HTTL3MBTL1RAB9AMAPTNPSR1 | |
| SCHEMBL4064696 | 0.75 | HTT (0.46) | HTTOPRM1L3MBTL1KDM4ERAB9A | |
| SCHEMBL11733824 | 0.74 | RAB9A (0.54) | HTTRAB9AMAPTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123264-A1 | Heterocyclic derivatives as abnormal cannabidiols agents for lowering intraocular pressure | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | claimed |