Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750717 | 0.81 | HTT (0.43) | HTTOPRM1THRBKDM4EL3MBTL1 | |
| SCHEMBL1750445 | 0.81 | NPBWR1 (0.44) | HTTOPRM1KDM4EMAPTLMNA | |
| SCHEMBL7754483 | 0.77 | MAPT (0.35) | HTTMAPTLMNAALOX12NPSR1 | |
| SCHEMBL4062470 | 0.75 | NPBWR1 (0.42) | CDK4CCND1LMNANPC1RAB9A | |
| SCHEMBL4063236 | 0.75 | HTT (0.43) | HTTOPRM1THRBKDM4EL3MBTL1 | |
| SCHEMBL11724179 | 0.74 | HTT (0.54) | HTTOPRM1THRBKDM4EL3MBTL1 | |
| SCHEMBL7755931 | 0.73 | PKM (0.43) | HTTL3MBTL1MAPTLMNANPSR1 | |
| SCHEMBL1750412 | 0.71 | MAPT (0.50) | HTTOPRM1THRBKDM4EL3MBTL1 | |
| SCHEMBL11734120 | 0.69 | KMT2A (0.50) | HTTOPRM1THRBKDM4EL3MBTL1 | |
| SCHEMBL1749799 | 0.69 | RAB9A (0.54) | HTTL3MBTL1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123264-A1 | Heterocyclic derivatives as abnormal cannabidiols agents for lowering intraocular pressure | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | claimed |