Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068204 | 0.93 | KDM4E (0.39) | KDM4EHSD17B10KMT2AF2ALOX15 | |
| SCHEMBL4241713 | 0.91 | FGFR3 (0.38) | KDM4EHSD17B10FGFR3NR1H2PTGES | |
| SCHEMBL4301158 | 0.90 | PTGES (0.36) | NR1H2EGFRKDRPTGESRIPK2 | |
| SCHEMBL4235750 | 0.89 | KDM4E (0.44) | KDM4EHSD17B10KMT2AF2ALOX15 | |
| SCHEMBL4057052 | 0.87 | DYRK3 (0.42) | FGFR3KMT2ANR1H2LMNAALDH1A1 | |
| SCHEMBL4232577 | 0.87 | FGFR3 (0.39) | FGFR3NR1H2KDRLMNACYP1A2 | |
| SCHEMBL4056602 | 0.86 | FGFR3 (0.39) | FGFR3NR1H2KDRLMNAALDH1A1 | |
| SCHEMBL4232436 | 0.85 | NR1H2 (0.36) | FGFR3NR1H2LMNAACACBHPGD | |
| SCHEMBL4231082 | 0.84 | NR1H2 (0.41) | NR1H2ALDH1A1TSHRCYP1A2CYP2C19 | |
| SCHEMBL4060823 | 0.83 | GRM5 (0.38) | KDM4EHSD17B10KMT2ANR1H2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |