Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057052 | 0.93 | DYRK3 (0.42) | FGFR3ALDH1A1NR1H2TSHRRAB9A | |
| SCHEMBL4231082 | 0.92 | NR1H2 (0.41) | ALDH1A1NR1H2TSHRCNR2RAB9A | |
| SCHEMBL4232436 | 0.92 | NR1H2 (0.36) | FGFR3NR1H2CNR2RAB9AHPGD | |
| SCHEMBL4232577 | 0.92 | FGFR3 (0.39) | FGFR3NR1H2CNR2RAB9AHPGD | |
| SCHEMBL4056602 | 0.92 | FGFR3 (0.39) | FGFR3ALDH1A1NR1H2TSHRCNR2 | |
| SCHEMBL4063530 | 0.91 | KDM4E (0.38) | FGFR3ALDH1A1NR1H2TSHRCNR2 | |
| SCHEMBL4233651 | 0.89 | PTGES (0.38) | NR1H2CNR2PTGES | |
| SCHEMBL4231079 | 0.86 | ALDH1A1 (0.38) | ALDH1A1NR1H2TSHRCNR2RAB9A | |
| SCHEMBL4303398 | 0.86 | CNR2 (0.38) | NR1H2CNR2PTGES | |
| SCHEMBL4068204 | 0.85 | KDM4E (0.39) | ALDH1A1NR1H2TSHRLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |