Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231079 | 0.91 | ALDH1A1 (0.38) | KDM4EHSD17B10RAB9ANPC1FAAH | |
| SCHEMBL4301152 | 0.90 | GRM5 (0.42) | GRM5CYP2C9PTGDR2NR1H2 | |
| SCHEMBL4057052 | 0.89 | DYRK3 (0.42) | GRM5EPHX2DYRK3DYRK1ADYRK2 | |
| SCHEMBL4065419 | 0.88 | ALDH1A1 (0.33) | KDM4EHSD17B10RAB9ANPC1KMT2A | |
| SCHEMBL4235750 | 0.87 | KDM4E (0.44) | KDM4EHSD17B10RAB9ANPC1KMT2A | |
| SCHEMBL4241719 | 0.83 | P2RY12 (0.35) | KDM4EHSD17B10RAB9ANPC1CYP2C9 | |
| SCHEMBL4063530 | 0.83 | KDM4E (0.38) | KDM4EHSD17B10RAB9AMEN1KMT2A | |
| SCHEMBL4241713 | 0.83 | FGFR3 (0.38) | KDM4EHSD17B10RAB9ANPC1CYP2C9 | |
| SCHEMBL4237158 | 0.82 | NR1H2 (0.35) | KDM4EHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL4242833 | 0.81 | PTPN1 (0.35) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |