Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848415 | 0.82 | ALDH1A1 (0.36) | HPGDRXRAALDH1A1HTTMAPK1 | |
| SCHEMBL4065989 | 0.81 | POLB (0.39) | HPGDLMNAMAPT | |
| SCHEMBL4068033 | 0.80 | MAPT (0.40) | GLRA1HPGDLMNARXRAALDH1A1 | |
| SCHEMBL30985926 | 0.79 | BRD4 (0.46) | NOTUMGLRA1HPGDLMNASMPD1 | |
| SCHEMBL22529568 | 0.79 | BRD4 (0.46) | NOTUMGLRA1HPGDLMNASMPD1 | |
| SCHEMBL13848295 | 0.78 | HPGD (0.48) | HPGDLMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL4071442 | 0.78 | BRD4 (0.38) | GLRA1HPGDLMNARXRAMAPT | |
| SCHEMBL19638242 | 0.78 | RXRA (0.41) | GLRA1RXRABRD4 | |
| SCHEMBL4072661 | 0.77 | GSK3B (0.43) | HPGDLMNAALDH1A1HTTMAPT | |
| SCHEMBL20427916 | 0.77 | ALDH1A1 (0.40) | GLRA1HPGDRXRASMPD1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |