Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248092 | 0.89 | POLB (0.45) | POLBHSD17B10MAPTHPGDTSHR | |
| SCHEMBL13848415 | 0.84 | ALDH1A1 (0.36) | HSD17B10HPGDTSHRKMT2AAAK1 | |
| SCHEMBL4058858 | 0.71 | P2RX3 (0.36) | HSD17B10MAPTHPGDLMNAP2RX3 | |
| SCHEMBL13848381 | 0.71 | RXRA (0.41) | KMT2A | |
| SCHEMBL4241628 | 0.71 | P2RX3 (0.49) | P2RX3P2RX2 | |
| SCHEMBL4246535 | 0.70 | MAPK14 (0.43) | LMNAIMPDH2P2RX3P2RX2 | |
| SCHEMBL17948750 | 0.69 | HPGD (0.41) | POLBHSD17B10MAPTHPGDTSHR | |
| SCHEMBL4070477 | 0.69 | TUBB4A (0.44) | HPGDKMT2AP2RX3P2RX2 | |
| SCHEMBL4060653 | 0.69 | TUBB4A (0.38) | HSD17B10MAPTHPGDLMNAP2RX3 | |
| SCHEMBL382174 | 0.69 | GAA (0.50) | POLBHSD17B10MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |