Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | GYS1 | P13807 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072687 | 0.79 | HSD17B10 (0.48) | LMNAHTTMCL1MAPK8GSK3B | |
| SCHEMBL13848474 | 0.76 | KCNK3 (0.51) | HTTABCB1KDM4EMEN1NPC1 | |
| SCHEMBL22354782 | 0.74 | SMN1; SMN2 (0.49) | HTTSMPD1CTSVCTSLHDAC1 | |
| SCHEMBL13848420 | 0.73 | ROCK1 (0.43) | GSK3BABCB1KDM4ENPC1RAB9A | |
| SCHEMBL16271509 | 0.73 | CTSV (0.45) | LMNAHTTSMPD1CTSVCTSL | |
| SCHEMBL22888386 | 0.73 | IKBKB (0.46) | PTGER1 | |
| SCHEMBL1019564 | 0.73 | HPGD (0.49) | LMNAHTTSMPD1CTSVCTSL | |
| SCHEMBL14512477 | 0.71 | MCL1 (0.58) | LMNAHTTMCL1CTSVCTSL | |
| SCHEMBL383740 | 0.71 | FOLH1 (0.55) | MCL1CTSVCTSLPTGER1KDM4E | |
| SCHEMBL1148717 | 0.70 | GLRA1 (0.49) | LMNAHTTSMPD1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |