Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848420 | 0.85 | ROCK1 (0.43) | KCNK3KCNK9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4072687 | 0.84 | HSD17B10 (0.48) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4066925 | 0.82 | BCL2 (0.52) | KCNK3KCNK9BCL2NPC1RAB9A | |
| SCHEMBL4064518 | 0.76 | LMNA (0.47) | NPC1RAB9AKMT2AMEN1HTT | |
| SCHEMBL4068175 | 0.75 | P2RX3 (0.47) | — | |
| SCHEMBL5786347 | 0.73 | KAT6A (0.58) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL4065128 | 0.73 | HSP90AA1 (0.46) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL4061388 | 0.72 | P2RX3 (0.46) | MAPTHPGD | |
| SCHEMBL4071802 | 0.72 | P2RX3 (0.47) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27316536 | 0.72 | P2RX3 (0.53) | MAPTHPGDS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |