Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395727 | 0.78 | CA1 (0.32) | — | |
| SCHEMBL4063029 | 0.72 | — | — | |
| SCHEMBL3922962 | 0.72 | CYP3A4 (0.33) | TSHR | |
| SCHEMBL120851 | 0.68 | ALDH1A1 (0.42) | ALDH1A1TSHR | |
| SCHEMBL1135594 | 0.68 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL29637482 | 0.68 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL133345 | 0.63 | TSHR (0.47) | ALDH1A1TSHR | |
| SCHEMBL29366549 | 0.63 | TSHR (0.47) | ALDH1A1TSHR | |
| SCHEMBL11045804 | 0.63 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL15063874 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030248-A1 | Ethynylphenylbiadamantane derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-2014636-A1 | Ethynylphenylbiadamantane derivatives | Daicel Chemical Industries, Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030248-A1 | Ethynylphenylbiadamantane derivatives | CHRNA5, CHRNE, ADRA1D | ALDH1A1 1329/4885TSHR 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.