Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 2/20 | 1.00 |
| ▸ | GAPDH | P04406 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | MAOB | P27338 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.71 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.71 |
| ▸ | MIF | P14174 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177366 | 0.86 | RAB9A (1.00) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL30356319 | 0.86 | RAB9A (1.00) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL22132746 | 0.85 | MAOB (0.82) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL29926826 | 0.85 | MAOB (0.82) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL2166723 | 0.85 | ESR2 (1.00) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL17807912 | 0.84 | ALDH1A1 (0.72) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL22132745 | 0.84 | GAPDH (1.00) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL14389070 | 0.83 | MAOB (0.75) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL2929526 | 0.83 | ALDH1A1 (0.75) | ALDH1A1RAB9AHPGDNPC1ESR2 | |
| SCHEMBL7124667 | 0.83 | KDM4E (0.75) | ALDH1A1RAB9AHPGDNPC1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118338-A2 | USE OF A POLYPHENOLIC TYPE COMPOUND FOR PREVENTING OR TREATING A POLYGLUTAMINE EXPANSION NEURODEGENERATIVE DISEASE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2009-10-01 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| CN-111378169-A | Force-induced response hybrid crosslinked dynamic polymer | 翁秋梅 | 2020-07-07 | — | — | CN | disclosed |
| WO-2020130120-A1 | CANCER METASTASIS INHIBITOR | 学校法人京都薬科大学 | 2020-06-25 | — | — | WO | disclosed |
| EP-2695930-B1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE, NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | DAINIPPON INK & CHEMICALS (JP) | 2019-09-11 | — | — | EP | disclosed |
| US-9475991-B2 | Polymerizable liquid crystal composition, polarized light-emitting coating material, novel naphtholactam derivative novel coumarin derivative, novel nile red derivative, and novel anthracene derivative | ADEKA CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| US-9475991-B2 | Polymerizable liquid crystal composition, polarized light-emitting coating material, novel naphtholactam derivative novel coumarin derivative, novel nile red derivative, and novel anthracene derivative | ADEKA CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| EP-2695930-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE, NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | Adeka Corporation (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-20130334461-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | ADEKA CORPORATION (JP) | 2013-12-19 | — | — | US | disclosed |
| US-20130334461-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE | ADEKA CORPORATION (JP) | 2013-12-19 | — | — | US | disclosed |
| WO-2009118338-A2 | USE OF A POLYPHENOLIC TYPE COMPOUND FOR PREVENTING OR TREATING A POLYGLUTAMINE EXPANSION NEURODEGENERATIVE DISEASE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2009-10-01 | — | — | WO | disclosed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |