Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | DCK | P27707 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068953 | 0.85 | MTNR1A (0.33) | TLR7TLR8 | |
| SCHEMBL5805143 | 0.84 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL4070545 | 0.84 | TLR8 (0.34) | TLR7TLR8 | |
| SCHEMBL5805491 | 0.79 | DCPS (0.38) | TLR7TLR8 | |
| SCHEMBL17181527 | 0.76 | TLR8 (0.37) | TLR7TLR8 | |
| SCHEMBL4520810 | 0.75 | TLR7 (0.34) | TLR7 | |
| SCHEMBL4073451 | 0.75 | TLR8 (0.31) | TLR7TLR8 | |
| SCHEMBL25959237 | 0.70 | TLR7 (0.42) | TLR7 | |
| SCHEMBL30662187 | 0.68 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL21712373 | 0.68 | TLR7 (0.51) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673087-A4 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1673087-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005032484-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |