Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 17/20 | 0.41 |
| ▸ | CDK9 | P50750 | 17/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4076052 | 1.00 | CCNT1 (0.41) | CCNT1CDK9PIK3CDPIK3CAPIK3CB | |
| SCHEMBL4251137 | 0.83 | CNR1 (0.50) | CCNT1CDK9 | |
| SCHEMBL4065269 | 0.83 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL4064016 | 0.75 | KCNH2 (0.39) | CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL4075207 | 0.75 | KCNH2 (0.39) | CCNT1CDK9 | |
| SCHEMBL16107306 | 0.70 | PDK4 (0.40) | CCNT1CDK9 | |
| SCHEMBL4068232 | 0.69 | CYP1A2 (0.47) | CCNT1CDK9PIK3CA | |
| SCHEMBL16135142 | 0.67 | PDK4 (0.58) | — | |
| SCHEMBL14516253 | 0.67 | MEN1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL6756852 | 0.66 | NNMT (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | disclosed |
| US-20060189601-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189601-A1 | Antibacterial agents | NQO2, NRDC, IFNG | CCNT1 2174/4885CDK9 3122/4885PIK3CD 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.