Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.43 |
| ▸ | CDK9 | P50750 | 14/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010093 | 0.76 | KDM4E (0.73) | CYP1A2CYP3A4KDM4EMEN1ALDH1A1 | |
| SCHEMBL12889425 | 0.71 | KDM4E (0.54) | CYP1A2CYP3A4KDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16423084 | 0.70 | HTR2C (0.46) | CYP1A2CYP3A4KDM4EMEN1ALDH1A1 | |
| SCHEMBL1222623 | 0.70 | NCF1 (0.57) | MAPTCYP2C19HTR6HTR2CDRD2 | |
| SCHEMBL3115300 | 0.70 | DYRK1A (0.48) | MAPK1PIK3CA | |
| SCHEMBL15884572 | 0.70 | RAF1 (0.44) | MEN1ALDH1A1MAPTKMT2APIK3CA | |
| Hydrochloric Acid SCHEMBL4076052 | 0.69 | CCNT1 (0.41) | CCNT1CDK9PIK3CA | |
| SCHEMBL4065093 | 0.69 | CCNT1 (0.41) | CCNT1CDK9PIK3CA | |
| SCHEMBL23411233 | 0.69 | QDPR (0.52) | HTR2CPIK3CAMTOR | |
| SCHEMBL31150129 | 0.69 | QDPR (0.52) | HTR2CPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | disclosed |
| US-20060189601-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189601-A1 | Antibacterial agents | NQO2, NRDC, IFNG | CYP1A2 1489/4885CYP3A4 873/4885KDM4E 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.