SCHEMBL4065292

SCHEMBL4065292

CC(C)(C)c1ccc(C(c2cc(Cl)c(O)cc2O)c2cc(Cl)c(O)cc2O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 4/20 0.38
TYR P14679 1/20 0.38
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
HSD17B2 P37059 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058186 0.81 HSD17B10 (0.38) ALDH1A1HPGDHSD17B10TDP1LMNA
SCHEMBL4066948 0.78 ESR2 (0.41) ALDH1A1HPGDHSD17B10TDP1LMNA
SCHEMBL4064362 0.77 ATM (0.41) TDP1LMNAKMT2ACNR1CNR2
SCHEMBL19806867 0.77 TYR (0.50) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL17570369 0.75 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL17977154 0.73 CA1 (0.45) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL22316274 0.72 LMNA (0.48) AKR1C2AKR1C1ALDH1A1HPGDALOX15
SCHEMBL51094 0.70 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL51009 0.70 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL292572 0.70 TSHR (0.52) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM AKR1C2 3087/4885AKR1C1 1971/4885ALDH1A1 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.