SCHEMBL4066948

SCHEMBL4066948

Oc1cc(O)c(C(c2ccccc2)c2cc(Cl)c(O)cc2O)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.41
TYR P14679 1/20 0.41
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
HSP90AA1 P07900 3/20 0.37
ALDH1A1 P00352 2/20 0.37
PDK1 Q15118 3/20 0.36
LMNA P02545 1/20 0.36
ACP3 P15309 1/20 0.36
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058186 0.85 HSD17B10 (0.38) ESR2TSHRHSD17B10HPGDHSP90AA1
SCHEMBL4063285 0.81 GABRA1 (0.42) ESR2TSHRHSD17B10HPGDHSP90AA1
SCHEMBL4064362 0.78 ATM (0.41) TSHRHSP90AA1LMNATDP1
SCHEMBL4065292 0.78 AKR1C2 (0.39) TYRHSD17B10HPGDALDH1A1LMNA
SCHEMBL51604 0.77 MEN1 (0.54) TSHRHSD17B10HPGDALDH1A1LMNA
SCHEMBL51321 0.77 TYR (0.44) TYRTSHRHSD17B10HPGDHSP90AA1
SCHEMBL25916200 0.76 TYR (0.43) TYRTDP1
SCHEMBL21087439 0.74 LMNA (0.36) ESR2TYRALDH1A1PDK1LMNA
SCHEMBL28295105 0.73 MEN1 (0.54) TSHRHSD17B10HPGDALDH1A1LMNA
SCHEMBL17977154 0.73 CA1 (0.45) HSD17B10HPGDHSP90AA1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ESR2 895/4885TYR 1522/4885TSHR 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.