Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231079 | 0.92 | ALDH1A1 (0.38) | ALDH1A1NR1H2KDM4EHSD17B10TSHR | |
| SCHEMBL4297916 | 0.89 | GABRG2 (0.35) | NR1H2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4060823 | 0.88 | GRM5 (0.38) | ALDH1A1NR1H2KDM4EHSD17B10TSHR | |
| SCHEMBL4232577 | 0.87 | FGFR3 (0.39) | NR1H2GAACYP1A2CYP2C19RAB9A | |
| SCHEMBL4238011 | 0.87 | NR1H2 (0.37) | ALDH1A1NR1H2TSHRGAARAB9A | |
| SCHEMBL4235750 | 0.86 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10TSHRGAA | |
| SCHEMBL4237158 | 0.83 | NR1H2 (0.35) | ALDH1A1NR1H2KDM4EHSD17B10TSHR | |
| SCHEMBL4241719 | 0.83 | P2RY12 (0.35) | ALDH1A1NR1H2KDM4EHSD17B10GAA | |
| SCHEMBL4242833 | 0.81 | PTPN1 (0.35) | NR1H2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4231082 | 0.81 | NR1H2 (0.41) | ALDH1A1NR1H2TSHRGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |