Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241719 | 0.94 | P2RY12 (0.35) | NR1H2KDM4EHSD17B10GAACYP1A2 | |
| SCHEMBL4062422 | 0.88 | TTK (0.38) | NR1H2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4231079 | 0.87 | ALDH1A1 (0.38) | NR1H2KDM4EHSD17B10GAACYP1A2 | |
| SCHEMBL4235750 | 0.85 | KDM4E (0.44) | KDM4EHSD17B10GAACYP1A2CYP2C19 | |
| SCHEMBL4239515 | 0.84 | KDM4E (0.39) | NR1H2KDM4EHSD17B10GAACYP1A2 | |
| SCHEMBL4065419 | 0.83 | ALDH1A1 (0.33) | NR1H2KDM4EHSD17B10GAACYP1A2 | |
| SCHEMBL4231082 | 0.82 | NR1H2 (0.41) | NR1H2GAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4060823 | 0.82 | GRM5 (0.38) | NR1H2KDM4EHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL4233655 | 0.82 | GABRA1 (0.38) | NR1H2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4242529 | 0.80 | GABRG2 (0.38) | NR1H2KDM4EGAACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |