Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063751 | 0.70 | MAPT (0.39) | PTPRCFFAR1MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL4062814 | 0.70 | GRIA2 (0.36) | ALDH1A1GAAMAPTKMT2AHTT | |
| SCHEMBL21772956 | 0.67 | PTPRC (0.52) | PTPRCFFAR1MAPK1ALDH1A1GAA | |
| SCHEMBL31034587 | 0.67 | CA12 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31650336 | 0.65 | MRGPRX4 (0.49) | HPGDLMNAMAPTHTTNPC1 | |
| SCHEMBL11821719 | 0.64 | RXRA (0.45) | PTPRCALDH1A1CYP2C9LMNAMAPT | |
| SCHEMBL1098130 | 0.64 | MCL1 (0.57) | MAPK1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22587561 | 0.64 | MAPT (0.52) | FFAR1MAPK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29445409 | 0.64 | MAPT (0.52) | FFAR1MAPK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28450966 | 0.64 | L3MBTL1 (0.51) | PTPRCFFAR1MAPK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330458-B1 | N-( 1,2,4 TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-06-03 | — | — | EP | disclosed |
| US-6645918-B1 | N-(Triazolo(1,5-a)pyrimidinyl)thiophenesulfonamide compounds; postemergence herbicides; agriculture | DOW AGROSCIENCES LLC | 2003-11-11 | — | — | US | disclosed |
| US-20030199393-A1 | N- ([1,2,4,] TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | ARNDT KIM ERIC (US) | 2003-10-23 | — | — | US | disclosed |
| EP-1330458-A1 | N-( 1,2,4]TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | Dow Agrosciences LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6518222-B2 | Prepared from 2-amino(1,2,4)triazolo(1,5-c)pyrimidine, 2-amino(1,2,4)triazolo(1,5-a)pyrimidine, and 2-amino(1,2,4)triazolo(1,5-a)pyridine compounds and thiophenesulfonyl chloride compounds | DOW AGROSCIENCES LLC | 2003-02-11 | — | — | US | disclosed |
| US-20020094935-A1 | N-([1,2,4] triazoloazinyl) thiophenesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC | 2002-07-18 | — | — | US | disclosed |
| WO-2002038572-A1 | N-([1,2,4]TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094935-A1 | N-([1,2,4] triazoloazinyl) thiophenesulfonamide compounds and their use as herbicides | PNPO, NAT1, DDT | PTPRC 983/4885FFAR1 3421/4885MAPK1 2411/4885 |
| US-20030199393-A1 | N- ([1,2,4,] TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | NAT1, TST, TASP1 | PTPRC 1463/4885FFAR1 2905/4885MAPK1 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.