SCHEMBL4065757

SCHEMBL4065757

CCc1cc(Cc2cc(C)c(O)c(C)c2)cc(Cc2cc(C)c(O)c(C)c2)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.58
HMGB1 P09429 1/20 0.50
CXCL12 P48061 1/20 0.50
DHFR P00374 2/20 0.47
PTPN1 P18031 2/20 0.41
PTPN2 P17706 1/20 0.41
PTPN6 P29350 1/20 0.41
HSPA5 P11021 1/20 0.41
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
ALOX5 P09917 1/20 0.40
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ALK Q9UM73 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30004950 1.00 SHBG (0.58) SHBGHMGB1CXCL12DHFRPTPN1
SCHEMBL2385253 1.00 SHBG (0.58) SHBGHMGB1CXCL12DHFRPTPN1
SCHEMBL30003742 0.96 SHBG (0.63) SHBGHMGB1CXCL12DHFRPTPN1
SCHEMBL2384360 0.96 SHBG (0.63) SHBGHMGB1CXCL12DHFRPTPN1
SCHEMBL4057392 0.92 SHBG (0.67) SHBGHMGB1CXCL12DHFRPTPN1
SCHEMBL7714483 0.92 SHBG (0.67) SHBGHMGB1CXCL12DHFRPTPN1
SCHEMBL15830868 0.91 SHBG (0.53) SHBGHMGB1CXCL12DHFRHSPA5
SCHEMBL7899901 0.91 SHBG (0.47) SHBGHMGB1CXCL12DHFRHSPA5
SCHEMBL3194655 0.90 SHBG (0.55) SHBGHMGB1CXCL12DHFRHSPA5
SCHEMBL69627 0.90 SHBG (0.70) SHBGHMGB1CXCL12DHFRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM SHBG 3960/4885HMGB1 196/4885CXCL12 2060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.