Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498935 | 0.83 | ALDH1A1 (0.40) | CTSSCTSBCTSLKMT2AMAPT | |
| SCHEMBL4061791 | 0.77 | APP (0.50) | APPCTSSCTSBCTSKPPARA | |
| SCHEMBL7951407 | 0.75 | SLC6A4 (0.40) | CTSSCTSBCTSKPPARAPTPN1 | |
| SCHEMBL14493068 | 0.74 | CTSB (0.47) | APPCTSSCTSBCTSKPPARA | |
| SCHEMBL3133276 | 0.74 | CTSS (0.56) | APPCTSSCTSBCTSKPPARA | |
| SCHEMBL20993818 | 0.74 | CTSS (0.56) | APPCTSSCTSBCTSKPPARA | |
| SCHEMBL6181712 | 0.74 | CTSS (0.56) | APPCTSSCTSBCTSKPPARA | |
| SCHEMBL16488769 | 0.74 | CTSS (0.56) | APPCTSSCTSBCTSKPPARA | |
| SCHEMBL13827783 | 0.74 | CTSS (0.56) | APPCTSSCTSBCTSKPPARA | |
| SCHEMBL3133278 | 0.74 | CTSS (0.56) | APPCTSSCTSBCTSKPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613338-A4 | TAMANDARIN ANALOGS AND FRAGMENTS THEREOF AND METHODS OF MAKING AND USING | JOULLIE MADELEINE M (US) | 2009-06-24 | — | — | EP | disclosed |
| EP-1613338-A2 | TAMANDARIN ANALOGS AND FRAGMENTS THEREOF AND METHODS OF MAKING AND USING | Joullie, Madeleine M. (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004084812-A2 | TAMANDARIN ANALOGS AND FRAGMENTS THEREOF AND METHODS OF MAKING AND USING | JOULLIE MADELEINE M (US) | 2004-10-07 | — | — | WO | disclosed |