Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.33 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072495 | 0.89 | CYP2C9 (0.35) | FTOALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1932047 | 0.72 | RAB9A (0.49) | ALDH1A1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL31068616 | 0.71 | CYP2A6 (0.42) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14872350 | 0.71 | CYP2A6 (0.42) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4066043 | 0.71 | NAPRT (0.51) | ALDH1A1CYP3A4CYP2C9CYP2C19TBXAS1 | |
| SCHEMBL4606675 | 0.69 | KDM4E (0.40) | ALDH1A1RAB9AKDM4EMAPT | |
| SCHEMBL27495542 | 0.69 | CA12 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19SRC | |
| SCHEMBL29951676 | 0.67 | CYP2E1 (0.44) | CYP3A4CYP2C9CYP2C19KDM4C | |
| SCHEMBL29958096 | 0.67 | AOC1 (0.35) | CYP2C19 | |
| SCHEMBL13387995 | 0.66 | KDM4C (0.39) | ALDH1A1KDM6BKDM4CRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751155-B1 | SUBSTITUTED AZACHINAZOLINES HAVING AN ANTIVIRAL ACTION | BAYER HEALTHCARE AG (DE) | 2009-01-07 | — | — | EP | disclosed |
| EP-1751155-A1 | SUBSTITUTED AZACHINAZOLINES HAVING AN ANTIVIRAL ACTION | Bayer HealthCare AG (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113552-A1 | SUBSTITUTED AZACHINAZOLINES HAVING AN ANTIVIRAL ACTION | BAYER HEALTHCARE AG (DE) | 2005-12-01 | — | — | WO | disclosed |