Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288813 | 0.72 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL4068784 | 0.71 | IFNAR1 (0.60) | MAOBMAOACA2ALDH1A1MAPT | |
| SCHEMBL22930554 | 0.71 | MAOB (0.40) | MAOBMAOAPTPN1FTOCA2 | |
| Hydrochloric Acid SCHEMBL4067559 | 0.70 | IFNAR1 (0.58) | MAOBMAOACA2ALDH1A1MAPT | |
| SCHEMBL4511347 | 0.70 | CYP1A2 (0.38) | MAOBCA2ALDH1A1 | |
| SCHEMBL4071116 | 0.69 | IFNAR1 (0.43) | MAOBMAOACA2ALDH1A1KDM4E | |
| SCHEMBL4071697 | 0.67 | IFNAR1 (0.42) | MAOBCA2ALDH1A1 | |
| SCHEMBL20651988 | 0.67 | MAOB (0.41) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL4070391 | 0.67 | IFNAR1 (0.41) | MAOBCA2ALDH1A1KDM4E | |
| SCHEMBL294155 | 0.66 | MAOB (0.56) | MAOBMAOAPTPN1FTOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534791-B2 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2009-05-19 | — | — | US | disclosed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | CYP1B1, TBCB, CYP4B1 | MAOB 14/4885MAOA 1004/4885PTPN1 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.