Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071697 | 0.82 | IFNAR1 (0.42) | MAOBCA2IFNAR1ALDH1A1LMNA | |
| SCHEMBL4070391 | 0.81 | IFNAR1 (0.41) | CYP1A2MAOBCA2SLC6A4IFNAR1 | |
| SCHEMBL4071116 | 0.79 | IFNAR1 (0.43) | MAOBCA2SLC6A4IFNAR1SLC6A2 | |
| SCHEMBL5237537 | 0.78 | CA2 (0.49) | CYP1A2CYP2D6CYP2C19MAOBCA2 | |
| SCHEMBL4068784 | 0.75 | IFNAR1 (0.60) | MAOBCA2SLC6A4IFNAR1SLC6A2 | |
| SCHEMBL4639280 | 0.75 | NQO2 (0.40) | MAOBCA2LMNA | |
| Hydrochloric Acid SCHEMBL4067559 | 0.74 | IFNAR1 (0.58) | MAOBCA2SLC6A4IFNAR1SLC6A2 | |
| SCHEMBL5235143 | 0.73 | CA2 (0.47) | CYP1A2CYP2D6CYP2C19MAOBCA2 | |
| SCHEMBL4067254 | 0.72 | GBA1 (0.35) | CYP1A2MAOBSLC6A4NPSR1ALDH1A1 | |
| SCHEMBL4071441 | 0.72 | GBA1 (0.35) | CYP1A2MAOBSLC6A4NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | H. LUNDBECK A/S (DK) | 2009-07-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | CYP1B1, TBCB, CYP4B1 | CYP1A2 165/4885CYP2D6 177/4885CYP2C19 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.