Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294155 | 0.82 | MAOB (0.56) | MAOBMAOAPTPN1FTOALDH1A1 | |
| SCHEMBL2490828 | 0.74 | CHRM2 (0.50) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL4066017 | 0.72 | MAOB (0.35) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL292528 | 0.71 | ALDH1A1 (0.38) | MAOBMAOAPTPN1FTOALDH1A1 | |
| SCHEMBL9109725 | 0.70 | POLB (0.53) | PTPN1ALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL24682836 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL276153 | 0.70 | MAOB (0.48) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL22955630 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL1311305 | 0.70 | NQO1 (0.48) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL12183 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313685-A1 | BROAD-SPECTRUM NON-COVALENT CORONAVIRUS PROTEASE INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2017-11-02 | — | — | US | claimed |
| CN-101932560-A | Matrix metalloproteinase inhibitors, pharmaceutical compositions containing them and their use | POISON MED INST PLA MED ACAD | 2010-12-29 | — | — | CN | claimed |
| US-20040254344-A1 | Amino acid conjugates providing for sustained systemic concentrations of gaba analogues | XENOPORT | 2004-12-16 | — | — | US | claimed |
| EP-1412324-A4 | AMINO ACID CONJUGATES PROVIDING FOR SUSTAINED SYSTEMIC CONCENTRATIONS OF GABA ANALOGUES | XENOPORT INC (US) | 2004-09-29 | — | — | EP | claimed |
| EP-1412324-A2 | AMINO ACID CONJUGATES PROVIDING FOR SUSTAINED SYSTEMIC CONCENTRATIONS OF GABA ANALOGUES | Xenoport, Inc. (US) | 2004-04-28 | — | — | EP | claimed |
| US-20030181390-A1 | Amino acid conjugates providing for sustained systemic concentrations of GABA analogues | XENOPORT, INC. | 2003-09-25 | — | — | US | claimed |
| WO-2002100344-A2 | AMINO ACID CONJUGATES PROVIDING FOR SUSTAINED SYSTEMIC CONCENTRATIONS OF GABA ANALOGUES | XENOPORT, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | claimed |
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | claimed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | claimed |
| EP-4334319-A1 | 2,8-DIHYDROPYRAZOLO[3,4-B]INDOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | Merck Patent GmbH (DE) | 2024-03-13 | — | — | EP | disclosed |
| CN-110092788-A | Substituted [1,2,4] triazol [1,5-a] pyrimidin-7-yl compound as PDE2 inhibitor | 达特神经科学(开曼)有限公司 | 2019-08-06 | — | — | CN | disclosed |
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |
| US-20180305373-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism BioLab Co., Ltd. (JP) | 2018-10-25 | — | — | US | disclosed |
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2018-07-10 | — | — | US | disclosed |
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254344-A1 | Amino acid conjugates providing for sustained systemic concentrations of gaba analogues | SLC6A1, SLC6A13, SLC6A11 | MAOB 747/4885MAOA 656/4885PTPN1 3477/4885 |
| US-20170313685-A1 | BROAD-SPECTRUM NON-COVALENT CORONAVIRUS PROTEASE INHIBITORS | ACE, ACE2, PEPD | MAOB 1507/4885MAOA 1355/4885PTPN1 1152/4885 |
| US-20180305373-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | MAOB 2988/4885MAOA 1729/4885PTPN1 2978/4885 |
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | PLOD3, COL1A1, THPO | MAOB 2988/4885MAOA 1729/4885PTPN1 2978/4885 |
| US-20030181390-A1 | Amino acid conjugates providing for sustained systemic concentrations of GABA analogues | SLC6A1, SLC6A13, SLC6A11 | MAOB 607/4885MAOA 536/4885PTPN1 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.