Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070391 | 0.96 | IFNAR1 (0.41) | IFNAR1PRMT1MEN1KMT2ACA2 | |
| SCHEMBL4071116 | 0.92 | IFNAR1 (0.43) | IFNAR1PRMT1CA2LMNARECQL | |
| SCHEMBL4068784 | 0.83 | IFNAR1 (0.60) | IFNAR1PRMT1MEN1KMT2ACA2 | |
| Hydrochloric Acid SCHEMBL4067559 | 0.82 | IFNAR1 (0.58) | IFNAR1MEN1KMT2ACA2LMNA | |
| SCHEMBL4511347 | 0.82 | CYP1A2 (0.38) | IFNAR1CA2LMNAMAOBALDH1A1 | |
| SCHEMBL4639280 | 0.77 | NQO2 (0.40) | CA2LMNARECQLSMN1; SMN2MAOB | |
| SCHEMBL4061582 | 0.75 | IFNAR1 (0.43) | IFNAR1PRMT1MEN1KMT2ACA2 | |
| SCHEMBL4387868 | 0.75 | HTR2A (0.55) | IFNAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL4234670 | 0.73 | NQO2 (0.47) | MEN1KMT2ALMNA | |
| SCHEMBL4395281 | 0.73 | GPR84 (0.44) | IFNAR1PRMT1MEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | H. LUNDBECK A/S (DK) | 2009-07-30 | — | — | US | claimed |
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | claimed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | claimed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | claimed |
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | H. LUNDBECK A/S (DK) | 2009-07-30 | — | — | US | disclosed |
| US-7534791-B2 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2009-05-19 | — | — | US | disclosed |
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | CYP1B1, TBCB, CYP4B1 | IFNAR1 2680/4885PRMT1 4749/4885MEN1 2561/4885 |
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | CYP1B1, TBCB, CYP4B1 | IFNAR1 2680/4885PRMT1 4749/4885MEN1 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.