SCHEMBL4066337

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11044755	0.75	MGLL (0.50)	MGLLHSD17B10KDM4ETSHRL3MBTL1
	SCHEMBL10560780	0.73	MGLL (0.48)	MGLLHSD17B10KDM4ETSHRL3MBTL1
	SCHEMBL30709623	0.73	MGLL (0.48)	MGLLHSD17B10KDM4ETSHRL3MBTL1
	SCHEMBL5175953	0.71	MGLL (0.46)	MGLLHSD17B10KDM4ETSHRL3MBTL1
	SCHEMBL11825229	0.68	MGLL (0.34)	MGLLHSD17B10KDM4ETSHRL3MBTL1
	SCHEMBL30070239	0.67	L3MBTL1 (0.59)	HSD17B10TSHRL3MBTL1ALOX15SMN1; SMN2
	SCHEMBL311608	0.67	L3MBTL1 (0.59)	HSD17B10TSHRL3MBTL1ALOX15SMN1; SMN2
	SCHEMBL16162461	0.63	SMN1; SMN2 (0.53)	MGLLKDM4ETSHRL3MBTL1SMN1; SMN2
	SCHEMBL4858555	0.62	L3MBTL1 (0.44)	GSK3BHSD17B10KDM4ETSHRL3MBTL1
	SCHEMBL7369109	0.62	CA12 (0.45)	GSK3BSMN1; SMN2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.