Propylene Oxide

Propylene Oxide

SCHEMBL4066375

CC1CO1.O=C(Oc1cccc(O)c1C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.52
ESR1 P03372 6/20 0.52
ESR2 Q92731 6/20 0.52
MAPT P10636 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
MEN1 O00255 3/20 0.52
GAA P10253 2/20 0.52
HSD17B10 Q99714 2/20 0.52
JAK2 O60674 1/20 0.52
USP2 O75604 1/20 0.52
ALOX15 P16050 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
SLC6A3 Q01959 1/20 0.43
POLB P06746 2/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SERPINE1 P05121 1/20 0.40
LMNA P02545 1/20 0.40
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78197 0.87 ESR1 (0.66) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL5672202 0.78 KMT2A (0.55) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL8399983 0.78 KMT2A (0.63) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL9807328 0.74 SERPINE1 (0.48) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL8619008 0.74 SLC6A3 (0.57) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL77853 0.74 NPSR1 (0.52) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL11740819 0.74 CA1 (0.58) KMT2AMAPTSMN1; SMN2MEN1HSD17B10
SCHEMBL844563 0.73 ESR1 (0.72) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL1918507 0.73 KMT2A (0.71) KMT2AESR1ESR2MAPTSMN1; SMN2
SCHEMBL2292938 0.72 ESR1 (0.66) KMT2AESR1ESR2MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0896963-B1 Methyl oxirane dibenzoylresorcinol UV absorbers MOMENTIVE PERFORMANCE MAT INC (US) 2009-10-21 EP disclosed
US-5959012-A COMPATIBILITY, SOLUBILITY, LOWER VOLATILITY, HIGHER MOLECULAR WEIGHT GENERAL ELECTRIC COMPANY (US) 1999-09-28 US disclosed
EP-0896963-A1 Methyl oxirane dibenzoylresorcinol UV absorbers GENERAL ELECTRIC COMPANY (US) 1999-02-17 EP disclosed