SCHEMBL77853

SCHEMBL77853

CC(C)(C)c1ccc(C(=O)Oc2cccc(O)c2C(=O)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.52
MAPT P10636 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ESR1 P03372 5/20 0.49
ESR2 Q92731 5/20 0.49
SIRT1 Q96EB6 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
JAK2 O60674 1/20 0.46
USP2 O75604 1/20 0.46
GAA P10253 1/20 0.46
ALOX15 P16050 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SRD5A2 P31213 1/20 0.45
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
HSD11B1 P28845 1/20 0.43
HSD17B3 P37058 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15390093 0.87 MAPT (0.54) NPSR1MAPTTDP1L3MBTL1ESR1
SCHEMBL8391960 0.84 NPSR1 (0.56) NPSR1MAPTTDP1L3MBTL1ESR1
SCHEMBL5350594 0.83 SIRT1 (0.61) MAPTTDP1SIRT1MEN1KMT2A
SCHEMBL78197 0.82 ESR1 (0.66) NPSR1MAPTESR1ESR2MEN1
SCHEMBL29045175 0.81 NPSR1 (0.47) NPSR1MAPTTDP1L3MBTL1ESR1
SCHEMBL20358249 0.78 NPSR1 (0.56) NPSR1MAPTTDP1L3MBTL1ESR1
SCHEMBL9807328 0.78 SERPINE1 (0.48) NPSR1MAPTTDP1L3MBTL1ESR1
SCHEMBL13292741 0.75 NPSR1 (0.59) NPSR1MAPTTDP1L3MBTL1MEN1
SCHEMBL5706010 0.75 NPSR1 (0.59) NPSR1MAPTTDP1L3MBTL1MEN1
Propylene Oxide SCHEMBL4066375 0.74 KMT2A (0.52) NPSR1MAPTESR1ESR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4806 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1953205-B1 Method for reducing the increase in dividing value during the manufacture of no label' look labels EVONIK GOLDSCHMIDT GMBH (DE) 2011-02-09 EP claimed
US-20080187702-A1 Method of reducing the increase in release force in the production of no-label-look labels EVONIK GOLDSCHMIDT GMBH (DE) 2008-08-07 US claimed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
EP-0142467-B1 POLYMER COMPOUNDS CONTAINING PIPERIDYL GROUPS AND THEIR USE AS STABILISERS IN SYNTHETIC POLYMERS CIBA-GEIGY S.p.A. (IT) 1988-08-24 EP claimed
EP-0140297-A2 Thiocarbamic-acid esters as stabilizers CIBA-GEIGY AG (CH) 1985-05-08 EP claimed
US-6391949-B1 None US disclosed
EP-4748878-A2 STERICALLY HINDERED AMINE STABILIZER MIXTURES BASF SE (DE) 2026-05-27 EP disclosed
EP-4748877-A2 STERICALLY HINDERED AMINE STABILIZER MIXTURES BASF SE (DE) 2026-05-27 EP disclosed
CN-117642406-B Phenol compound, stabilizer for organic material, resin composition, and method for stabilizing organic material SUMITOMO CHEMICAL CO.,LTD. (JP) 2026-05-26 CN disclosed
EP-4536463-B1 PROCESS TO PREPARE THERMOPLASTIC COMPOSITIONS COMPRISING FLUORINE FREE POLYMER PROCESSING AIDS NOVA CHEMICALS INTERNATIONAL SA (CH) 2026-05-13 EP disclosed
US-20260117044-A1 PHENOLIC COMPOUND, ORGANIC MATERIAL STABILIZER, RESIN COMPOSITION, AND METHOD FOR STABILIZING ORGANIC MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-04-30 US disclosed
US-20260109838-A1 CO-STABILIZERS FOR HYDROXYPHENYL TRIAZINE STABILIZED POLYMERS BASF SE (DE) 2026-04-23 US disclosed
US-4288391-A STABILIZERS FOR POLYMERS AND LUBRICANTS CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
US-4214088-A STABILIZERS FOR THERMOPLASTIC RESINS CIBA-GEIGY CORPORATION (US) 1980-07-22 US disclosed
EP-0002007-A1 Pyridine dicarboxylic acid derivatives, their mixtures with metallic stabilisers and their use in stabilising chlorine-containing thermoplasts CIBA-GEIGY AG (CH) 1979-05-30 EP disclosed
US-4141883-A Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives SANKYO COMPANY, LIMITED (JP) 1979-02-27 US disclosed
US-4097587-A 1,3,8-Triazaspiro 4.5!decane-2,4-dione polymer stabilizers SANKYO COMPANY, LIMITED (JA) 1978-06-27 US disclosed
US-4075165-A 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed
US-4007158-A 9-AZA- 1,5-DIOXA-SPIRO (5,5) UNDECANES SANKYO COMPANY LIMITED (JA) 1977-02-08 US disclosed
US-4000112-A POLYOLEFINS, TURBINE OILS CIBA-GEIGY CORPORATION (US) 1976-12-28 US disclosed