Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.49 |
| ▸ | GOT1 | P17174 | 1/20 | 0.49 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.49 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CCKBR | P32239 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075043 | 0.89 | CHRM2 (0.56) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4075145 | 0.89 | CHRM2 (0.53) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4066622 | 0.86 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL4250747 | 0.86 | SMN1; SMN2 (0.55) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4066762 | 0.86 | PYGL (0.54) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4064775 | 0.83 | PYGL (0.52) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4069399 | 0.81 | CHRM2 (0.48) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4072868 | 0.80 | L3MBTL1 (0.46) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4073097 | 0.80 | CHRM2 (0.51) | AADATGOT1KYAT1KYAT3CHRM2 | |
| SCHEMBL4891481 | 0.79 | AADAT (0.59) | AADATGOT1KYAT1KYAT3PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |