SCHEMBL4066635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2741825	0.83	HCAR3 (0.54)	HPGDHCAR3MLYCD
	SCHEMBL2884485	0.80	HCAR3 (0.53)	HPGDHCAR3MAPTPOLBSMN1; SMN2
	SCHEMBL29809047	0.78	CHRNA7 (0.42)	HPGDMAPTALDH1A1SMN1; SMN2RAB9A
	SCHEMBL20239526	0.78	CHRNA7 (0.42)	HPGDMAPTALDH1A1SMN1; SMN2RAB9A
	SCHEMBL1256199	0.77	HCAR3 (0.76)	HPGDHCAR3MAPTPOLBSMN1; SMN2
	SCHEMBL12349868	0.77	HCAR3 (0.57)	HPGDHCAR3MAPTALDH1A1MAPK1
	SCHEMBL14852264	0.77	NPC1 (0.39)	MAPTALDH1A1POLBSMN1; SMN2RAB9A
	SCHEMBL29751355	0.76	HCAR3 (0.55)	HPGDHCAR3MAPTALDH1A1MAPK1
	SCHEMBL4242678	0.74	LGALS8 (0.41)	ALDH1A1MLYCD
	SCHEMBL31132754	0.73	PDE2A (0.50)	HPGDHCAR3MAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.