Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | ATF4 | P18848 | 2/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742467 | 0.86 | ALDH1A1 (0.38) | CTSDBACE1HTR2ASLC6A4KCNH2 | |
| SCHEMBL1743116 | 0.81 | MEN1 (0.35) | GAAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL3711750 | 0.80 | HTR2A (0.40) | CTSDBACE1HTR2ASLC6A4KCNH2 | |
| SCHEMBL402927 | 0.79 | TP53 (0.34) | HTR2ASLC6A4KCNH2ALDH1A1KMT2A | |
| SCHEMBL10192853 | 0.77 | HTR2A (0.38) | CTSDBACE1HTR2ASLC6A4KCNH2 | |
| SCHEMBL416156 | 0.76 | MMP14 (0.36) | CTSDBACE1HTR2ASLC6A4KCNH2 | |
| SCHEMBL413841 | 0.76 | MMP14 (0.42) | SLC6A4KCNH2HIF1A | |
| SCHEMBL10195113 | 0.74 | HTR2A (0.37) | CTSDBACE1HTR2ASLC6A4KCNH2 | |
| SCHEMBL419430 | 0.73 | CTSD (0.40) | CTSDBACE1HTR2ASLC6A4KCNH2 | |
| SCHEMBL406549 | 0.72 | MAPK1 (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102642-B2 | Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and methods of controlling weeds | SYNGENTA LIMITED (GB) | 2015-08-11 | — | — | US | disclosed |
| EP-2393796-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| US-20120021909-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2393796-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089211-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021909-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | CTSD 3465/4885BACE1 1901/4885HTR2A 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.