Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416156 | 0.90 | MMP14 (0.36) | ALDH1A1PPARGMMP14MMP13MAOA | |
| SCHEMBL406720 | 0.86 | CTSD (0.40) | ALDH1A1PPARGHTR2ASLC6A4KCNH2 | |
| SCHEMBL1743116 | 0.82 | MEN1 (0.35) | ALDH1A1GAALMNA | |
| SCHEMBL406309 | 0.80 | CYP1A2 (0.42) | ALDH1A1PPARGHTR2ASLC6A4KCNH2 | |
| SCHEMBL515650 | 0.79 | ALDH1A1 (0.40) | ALDH1A1PPARGMMP14MMP13MAOA | |
| SCHEMBL1743662 | 0.79 | CCR6 (0.34) | ALDH1A1PPARGMAOAMAOBADAMTS5 | |
| SCHEMBL411018 | 0.76 | PNLIP (0.36) | ALDH1A1PPARGMMP14MMP13MAOA | |
| SCHEMBL402927 | 0.76 | TP53 (0.34) | ALDH1A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL405714 | 0.76 | ANPEP (0.39) | ALDH1A1GAALMNA | |
| SCHEMBL3034996 | 0.75 | PGR (0.40) | ALDH1A1TAAR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387569-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-11-23 | — | — | EP | disclosed |
| WO-2010081755-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |