Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 6/20 | 0.35 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213016 | 0.92 | THRB (0.38) | ALDH1A1KDM4EMEN1KMT2ATHRB | |
| SCHEMBL3222209 | 0.85 | THRB (0.36) | ALDH1A1THRBTHRARORCMTNR1A | |
| SCHEMBL3225634 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2ATHRB | |
| SCHEMBL3233002 | 0.83 | RORC (0.55) | THRBTHRARORC | |
| SCHEMBL3226662 | 0.83 | PPARG (0.41) | ALDH1A1THRBTHRALMNAMAPT | |
| SCHEMBL3224353 | 0.82 | THRB (0.41) | ALDH1A1KDM4EMEN1KMT2ATHRB | |
| SCHEMBL3227188 | 0.82 | THRB (0.46) | ALDH1A1THRBTHRARORC | |
| SCHEMBL3223228 | 0.81 | THRB (0.36) | ALDH1A1MEN1KMT2ATHRBTHRA | |
| SCHEMBL3227779 | 0.81 | TSHR (0.38) | ALDH1A1MEN1KMT2ATHRBTHRA | |
| SCHEMBL3219867 | 0.80 | THRB (0.40) | ALDH1A1KDM4EMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079678-A2 | SELECTIVE TR-BETA 1 AGONIST | Cadila Healthcare Limited (IN) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008062469-A2 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |