SCHEMBL4067415

SCHEMBL4067415

CC(=O)OCCS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
KMT2A Q03164 7/20 0.54
LMNA P02545 2/20 0.51
CA2 P00918 1/20 0.51
GAA P10253 2/20 0.49
PAX8 Q06710 1/20 0.48
MEN1 O00255 2/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14578756 0.88 ALDH1A1 (0.58) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL7239944 0.87 ALDH1A1 (0.59) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL15833291 0.86 CA2 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL12237305 0.85 GAA (0.51) ALDH1A1KMT2ALMNACA2GAA
SCHEMBL114044 0.85 ALDH1A1 (0.57) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL3298234 0.85 ALDH1A1 (0.55) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL14578750 0.85 LMNA (0.61) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL5711929 0.85 CA2 (0.54) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL8752139 0.85 CA2 (0.54) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL12237322 0.84 CA2 (0.53) ALDH1A1KMT2ALMNACA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10731004-B2 Polyimide precursor composition and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-08-04 US disclosed
US-10696793-B2 Process for preparing polyimides ETERNAL MATERIALS CO., LTD. (TW) 2020-06-30 US disclosed
US-10626220-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-04-21 US disclosed
US-20200055986-A1 PROCESS FOR PREPARING POLYIMIDES ETERNAL MATERIALS CO., LTD. (TW) 2020-02-20 US disclosed
US-20180148544-A1 PRECURSOR FOR POLYIMIDE AND USE THEREOF ETERNAL MATERIAL CO., LTD. (TW) 2018-05-31 US disclosed
US-20180148541-A1 POLYIMIDE PRECURSOR COMPOSITION AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-05-31 US disclosed
US-20180148541-A1 POLYIMIDE PRECURSOR COMPOSITION AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-05-31 US disclosed
US-20180148544-A1 PRECURSOR FOR POLYIMIDE AND USE THEREOF ETERNAL MATERIAL CO., LTD. (TW) 2018-05-31 US disclosed
US-20160367091-A9 Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using THE PROCTER & GAMBLE COMPANY 2016-12-22 US disclosed
US-9387254-B2 Prodrugs and drug-macromolecule conjugates having controlled drug release rates PROLYNX LLC (US) 2016-07-12 US disclosed
CN-101503394-B High piperazine acetydrazide derivatives, and preparation and use thereof SHENZHEN XIANGYA BIOLOGY MEDICAMENT ACADEMY 2010-05-12 CN disclosed
WO-2010034832-A1 MONOAZO DYES FOR DYEING LEATHER BASF SE (DE) 2010-04-01 WO disclosed
CN-101503394-A High piperazine acetydrazide derivatives, and preparation and use thereof SHENZHEN XIANGYA BIOLOGY MEDIC (CN) 2009-08-12 CN disclosed
US-7550458-B2 Tricycloundecane compounds useful as modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2009-06-23 US disclosed
US-20070234488-A1 Method for the Reactive Coloration of Leather BASF AKTIENGESELLSCHAFT (DE) 2007-10-11 US disclosed
US-20070088029-A1 Tricycloundecane compounds useful as modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY 2007-04-19 US disclosed
EP-1556371-B1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR WINSTON PHARMACEUTICALS LLC (US) 2006-04-19 EP disclosed
EP-1556371-A2 BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR Winston Pharmaceuticals LLC (US) 2005-07-27 EP disclosed
CN-1523989-A Macrophage migration inhibitory factor inhibitor and identification method thereof ������˹ҩƷ��˾ 2004-08-25 CN disclosed
WO-2004009583-A2 BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR GARST MICHAEL E (US) 2004-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070088029-A1 Tricycloundecane compounds useful as modulators of nuclear hormone receptor function VDR, ESRRB, NR5A1 ALDH1A1 3634/4885CYP3A4 628/4885CYP2C9 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.