SCHEMBL4067426

SCHEMBL4067426

CC(CC(C)C)=C1C(=O)CC(C)(C)CC1=O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.40
MAPT P10636 4/20 0.40
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PTGES O14684 2/20 0.37
ALOX5 P09917 2/20 0.37
NPSR1 Q6W5P4 2/20 0.36
TSHR P16473 1/20 0.35
MAOA P21397 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22271945 0.84 KDM4E (0.41) ALDH1A1TDP1LMNAKDM4E
SCHEMBL12018164 0.82 POLB (0.41) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL19130728 0.81 POLB (0.41) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL17336270 0.79 PTGES (0.39) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL17002051 0.78 POLB (0.39) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL13840142 0.78 ALDH1A1 (0.44) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL23483021 0.77 ALDH1A1 (0.40) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL19404324 0.77 TDP1 (0.41) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL24455557 0.77 SMN1; SMN2 (0.43) ALDH1A1MAPTPOLBSMN1; SMN2TDP1
SCHEMBL12444834 0.75 SMN1; SMN2 (0.34) ALDH1A1MAPTPOLBSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4010352-B1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES GYROS PROTEIN TECH AB (SE) 2023-10-18 EP disclosed
EP-4219446-A2 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Gyros Protein Technologies AB (SE) 2023-08-02 EP disclosed
WO-2021136808-A1 CONJUGATES UNDERGOING INTRAMOLECULAR REARRANGEMENTS ASCENDIS PHARMA A/S (DK) 2021-07-08 WO disclosed
US-20210171437-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO VERA THERAPEUTICS INC (US) 2021-06-10 US disclosed
WO-2020043747-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Belyntic GmbH (DE) 2020-03-05 WO disclosed
US-20190055190-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO NEUBASE THERAPEUTICS, INC. 2019-02-21 US disclosed
US-20170276686-A1 SINGLE MOLECULE PEPTIDE SEQUENCING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2017-09-28 US disclosed
US-20170204138-A1 ANTIBACTERIAL AGENTS THE UNIVERSITY OF QUEENSLAND (AU) 2017-07-20 US disclosed
US-20160367091-A9 Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using THE PROCTER & GAMBLE COMPANY 2016-12-22 US disclosed
US-20160367091-A9 Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using THE PROCTER & GAMBLE COMPANY 2016-12-22 US disclosed
WO-2011112887-A1 DI-AMIDO GELLANT FOR USE IN CONSUMER PRODUCT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2011-09-15 WO disclosed
US-20110220536-A1 Fluid Detergent Compositions Comprising a Di-Amido Gellant, and Processes for Making THE PROCTER & GAMBLE COMPANY 2011-09-15 US disclosed
WO-2011112886-A1 FLUID DETERGENT COMPOSITIONS COMPRISING A DI-AMIDO GELLANT, AND PROCESSES FOR MAKING THE PROCTER & GAMBLE COMPANY (US) 2011-09-15 WO disclosed
US-20110220536-A1 Fluid Detergent Compositions Comprising a Di-Amido Gellant, and Processes for Making THE PROCTER & GAMBLE COMPANY 2011-09-15 US disclosed
US-20110224455-A1 Di-Amido Gellant For Use In Consumer Product Compositions THE PROCTER & GAMBLE COMPANY 2011-09-15 US disclosed
EP-2365051-A1 Fluid detergent compositions comprising a di-amido gellant, and process for making The Procter & Gamble Company (US) 2011-09-14 EP disclosed
EP-2365050-A1 Di-amido gelaant for use in consumer product compositions The Procter & Gamble Company (US) 2011-09-14 EP disclosed
US-20100260672-A1 PEPTIDES THAT SPECIFICALLY BIND HGF RECEPTOR (CMET) AND USES THEREOF DYAX CORP. (US) 2010-10-14 US disclosed
WO-2007120614-A2 HOMOGENEOUS ERYTHROPOIETIN AND OTHER PEPTIDES AND PROTEINS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2007-10-25 WO disclosed
US-7211240-B2 Multivalent constructs for therapeutic and diagnostic applications BRACCO INTERNATIONAL B.V. (NL) 2007-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190055190-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO TARBP1, TIA1, SSB ALDH1A1 4569/4885MAPT 2325/4885POLB 421/4885
US-20210171437-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO TARBP1, TIA1, SSB ALDH1A1 4569/4885MAPT 2325/4885POLB 421/4885
US-20170204138-A1 ANTIBACTERIAL AGENTS VNN1, ASNS, AAAS ALDH1A1 4427/4885MAPT 4603/4885POLB 1399/4885
US-20110224455-A1 Di-Amido Gellant For Use In Consumer Product Compositions DAGLA, GNPAT, CDIPT ALDH1A1 1506/4885MAPT 1057/4885POLB 2941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.