Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783299 | 0.80 | CA1 (0.46) | CA1CA2 | |
| SCHEMBL11214230 | 0.78 | CA1 (0.43) | CA1CA2 | |
| SCHEMBL23480444 | 0.74 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL5018108 | 0.74 | — | — | |
| SCHEMBL4407815 | 0.72 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL21677099 | 0.72 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL20988207 | 0.70 | — | — | |
| SCHEMBL21885778 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL22361443 | 0.69 | LMNA (0.31) | — | |
| SCHEMBL24961528 | 0.67 | CA1 (0.33) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| EP-1226127-B1 | SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-6849618-B2 | Uracil substituted phenyl sulfamoly carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CARLSEN MARIANNE | 2004-11-04 | — | — | US | disclosed |
| US-6689773-B2 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CARLSEN MARIANNE (US) | 2003-12-04 | — | — | US | disclosed |
| US-6534492-B2 | Herbicidal phenylsulfamoyl carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-1226127-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) | 2002-04-18 | — | — | US | disclosed |
| WO-2001083459-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | CA1 1413/4885CA2 1329/4885 |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | CA1 4829/4885CA2 3312/4885 |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | CA1 1413/4885CA2 1329/4885 |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CBR3, HDHD5, DDAH1 | CA1 772/4885CA2 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.