Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059399 | 0.88 | CES2 (0.38) | ALDH1A1PSMB5CES2CES1LMNA | |
| SCHEMBL4063502 | 0.83 | LAP3 (0.34) | PSMB5FOLH1LAP3CACNA2D1CACNB3 | |
| SCHEMBL1781366 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CES2CES1FFAR3HDAC3 | |
| SCHEMBL17949830 | 0.73 | CES2 (0.39) | ALDH1A1PSMB5CES2CES1FFAR3 | |
| SCHEMBL17909924 | 0.73 | — | — | |
| SCHEMBL14560234 | 0.73 | LAP3 (0.36) | ALDH1A1FOLH1LAP3CACNA2D1CACNB3 | |
| SCHEMBL1781745 | 0.73 | LAP3 (0.36) | ALDH1A1FOLH1LAP3CACNA2D1CACNB3 | |
| SCHEMBL13461523 | 0.73 | LAP3 (0.48) | ALDH1A1FOLH1LAP3CACNA2D1CACNB3 | |
| SCHEMBL8072286 | 0.73 | LAP3 (0.48) | ALDH1A1FOLH1LAP3CACNA2D1CACNB3 | |
| SCHEMBL13554998 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LAP3TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |