Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560234 | 1.00 | LAP3 (0.36) | LAP3ALDH1A1TDP1RNPEPSLC7A5 | |
| SCHEMBL1782678 | 0.89 | KISS1R (0.32) | LAP3ALDH1A1TDP1RNPEPSLC7A5 | |
| SCHEMBL11323974 | 0.83 | KISS1R (0.31) | KISS1R | |
| SCHEMBL1784715 | 0.81 | — | — | |
| SCHEMBL8072286 | 0.80 | LAP3 (0.48) | LAP3ALDH1A1RNPEPSLC7A5CACNA2D1 | |
| SCHEMBL13461523 | 0.80 | LAP3 (0.48) | LAP3ALDH1A1RNPEPSLC7A5CACNA2D1 | |
| SCHEMBL1782972 | 0.79 | MAPT (0.30) | — | |
| SCHEMBL13554081 | 0.78 | LAP3 (0.35) | LAP3ALDH1A1TDP1RNPEPSLC7A5 | |
| SCHEMBL6904512 | 0.78 | TSHR (0.46) | LAP3ALDH1A1TDP1RNPEPSLC7A5 | |
| SCHEMBL1784171 | 0.78 | CA1 (0.36) | ALDH1A1TDP1KISS1RTSHRSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159580-A1 | PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) | VERTEX PHARMACEUTICALS INCORPORATED | 2023-05-25 | — | — | US | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8067136-B2 | Charge control agent, toner, image forming method, and image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| US-7589156-B2 | Polyhydroxyalkanoic acid having ester, carboxyl or sulfonic acid group, and producing method therefor | CANON KABUSHIKI KAISHA (JP) | 2009-09-15 | — | — | US | disclosed |
| US-20090202927-A1 | Charge control agent, toner, image forming method, and image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2009-08-13 | — | — | US | disclosed |
| US-7510813-B2 | Resin-coated carrier for electrophotographic developer | CANON KABUSHIKI KAISHA (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7273734-B2 | Process for producing a polyester | CANON KABUSHIKI KAISHA (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20070117937-A1 | Polyhydroxyalkanoic acid having ester, carboxyl or sulfonic acid group and producing method thereor | CANON KABUSHIKI KAISHA (JP) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | LAP3 4807/4885ALDH1A1 520/4885TDP1 3995/4885 |
| US-20230159580-A1 | PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) | SERPINA2, SERPINA3, SERPINC1 | LAP3 321/4885ALDH1A1 508/4885TDP1 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.