SCHEMBL4068898

SCHEMBL4068898

CCOCc1nc2c(N)nc3cc(O)cc(CC(C)C)c3c2[nH]1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586839 0.73 TLR7 (0.38) TLR7
SCHEMBL9043184 0.72
SCHEMBL30662197 0.72 TLR8 (0.43) TLR7
SCHEMBL5504493 0.72 ADORA2A (0.40) TLR7
SCHEMBL21712357 0.72 TLR8 (0.43) TLR7
SCHEMBL6220080 0.71 TLR8 (0.33) TLR7
SCHEMBL5814483 0.71 ELANE (0.32) TLR7
SCHEMBL4069055 0.71 PRMT5 (0.34)
SCHEMBL4654594 0.71 TLR7 (0.39) TLR7
SCHEMBL4073451 0.71 TLR8 (0.31) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1658076-A4 ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2009-02-25 EP disclosed
EP-1658076-A1 ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2006-05-24 EP disclosed
WO-2005020999-A1 ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-03-10 WO disclosed