Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291496 | 0.94 | SLC18A3 (0.41) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL9184270 | 0.87 | SLC18A3 (0.40) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL9184275 | 0.87 | SLC18A3 (0.40) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL1405569 | 0.85 | ESR2 (0.50) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL2537599 | 0.80 | SLC18A3 (0.52) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL43080 | 0.80 | SLC18A3 (0.56) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL29097441 | 0.79 | ALDH1A1 (0.41) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL346325 | 0.78 | LMNA (0.59) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL8025878 | 0.78 | LMNA (0.59) | SLC18A3ALDH1A1MAPTLMNATP53 | |
| SCHEMBL28722738 | 0.78 | LMNA (0.59) | SLC18A3ALDH1A1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| US-5380462-A | Cyclohexyl alkenoate compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-01-10 | — | — | US | disclosed |