SCHEMBL43080

SCHEMBL43080

Cc1ccc(C2CCCC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.56
LMNA P02545 3/20 0.56
ALDH1A1 P00352 3/20 0.56
MAPT P10636 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
TP53 P04637 1/20 0.56
ATM Q13315 1/20 0.56
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HTT P42858 4/20 0.42
XBP1 P17861 1/20 0.42
RAB9A P51151 3/20 0.42
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ESR2 Q92731 2/20 0.42
NPC1 O15118 1/20 0.42
NOTUM Q6P988 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28722738 0.97 LMNA (0.59) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL8025878 0.97 LMNA (0.59) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL346325 0.97 LMNA (0.59) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL2537599 0.95 SLC18A3 (0.52) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL18117721 0.91 MAPT (0.54) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL1405569 0.89 ESR2 (0.50) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
Bicarbonate SCHEMBL9685458 0.89 SLC18A3 (0.53) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL1417522 0.87 LMNA (0.51) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL11282272 0.87 SLC18A3 (0.51) SLC18A3LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL781509 0.86 HDAC1 (0.54) LMNAMAPTHDAC1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059683-A Synthetic heat conduction oil and application 中国石油化工股份有限公司 2025-05-30 CN claimed
CN-120059684-A Raw material composition for organic synthesis reaction, application thereof, hydrogenated terphenyl synthetic heat conduction oil and preparation method thereof 中国石油化工股份有限公司 2025-05-30 CN claimed
US-10710945-B2 Aromatic compositions and methods for obtaining them EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-07-14 US claimed
WO-2019201698-A1 A MOLDABLE REINFORCED THERMOPLASTIC POLYURETHANE, A PROCESS FOR PREPARING THE SAME, AND AN ARTICLE OBTAINED THEREFROM EXHIBITING HIGH MODULUS, LOW CREEP AND HIGH FATIGUE LIFE BASF SE (DE) 2019-10-24 WO claimed
US-10259759-B2 Cyclohexylbenzene composition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-04-16 US claimed
US-20180237361-A1 Aromatic Compositions and Methods for Obtaining Them EXXONMOBIL CHEMICAL PATENTS INC. 2018-08-23 US claimed
US-9908829-B2 Process for making phenol and/or cyclohexanone EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-03-06 US claimed
WO-2017052790-A1 AROMATIC COMPOSITIONS AND METHODS FOR OBTAINING THEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-30 WO claimed
US-20170057895-A1 Phenol Composition EXXONMOBIL CHEMICAL PATENTS INC. 2017-03-02 US claimed
US-20170001930-A1 Cyclohexylbenzene Composition EXXONMOBIL CHEMICAL PATENTS INC. 2017-01-05 US claimed
US-20110015457-A1 Process for Producing Cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US claimed
WO-2010098916-A2 PROCESS FOR PRODUCING PHENOL EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-09-02 WO claimed
WO-2009128984-A1 PROCESS FOR PRODUCING CYCLOHEXYLBENZENE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-10-22 WO claimed
EP-1569512-B1 PARTICULATE SUSPENSIONS SYNGENTA LTD (GB) 2007-02-28 EP claimed
US-7115654-B2 Caspase-1 inhibitors and methods for their use SUNESIS PHARMACEUTICALS, INC. (US) 2006-10-03 US claimed
EP-1193277-B1 Water dispersable blocked polyisocyanate adducts in powder form, a process for their preparation and their use DEGUSSA (DE) 2006-03-22 EP claimed
US-6790267-B1 METHINE COLORANT COMPOUNDS FOR PHASE CHANGE INKS XEROX CORPORATION 2004-09-14 US claimed
US-20040048895-A1 Caspase-1 inhibitors and methods for their use SUNESIS PHARMACEUTICALS, INC. 2004-03-11 US claimed
WO-2003103599-A2 CASPASE-1 INHIBITORS AND METHODS FOR THEIR USE SUNESIS PHARMACEUTICALS, INC. (US) 2003-12-18 WO claimed
WO-2001002375-A1 PROCESS FOR SYNTHESIZING OXADIAZOLES CHEMRX ADVANCED TECHNOLOGIES, INC. (US) 2001-01-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180237361-A1 Aromatic Compositions and Methods for Obtaining Them AHR, ARNT, TDO2 SLC18A3 1054/4885LMNA 2247/4885ALDH1A1 1046/4885
US-10259759-B2 Cyclohexylbenzene composition CYP1B1, CYP4B1, MCCC2 SLC18A3 3189/4885LMNA 1871/4885ALDH1A1 2579/4885
US-20170001930-A1 Cyclohexylbenzene Composition CYP1B1, CYP4B1, MCCC2 SLC18A3 3189/4885LMNA 1871/4885ALDH1A1 2579/4885
US-20170057895-A1 Phenol Composition CYP4B1, CYP26B1, CYP1B1 SLC18A3 2832/4885LMNA 2024/4885ALDH1A1 2046/4885
US-20040048895-A1 Caspase-1 inhibitors and methods for their use CASP1, CASP2, CASP9 SLC18A3 4884/4885LMNA 177/4885ALDH1A1 719/4885
US-10710945-B2 Aromatic compositions and methods for obtaining them AHR, ARNT, TDO2 SLC18A3 1054/4885LMNA 2247/4885ALDH1A1 1046/4885
US-20110015457-A1 Process for Producing Cyclohexylbenzene MCM2, MCM4, MCM6 SLC18A3 2920/4885LMNA 2330/4885ALDH1A1 4168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.