Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065692 | 0.99 | KDR (0.43) | MCHR1KCNH2KDRHRH3HPGD | |
| SCHEMBL4061393 | 0.93 | EPHX2 (0.44) | MCHR1SCN9A | |
| SCHEMBL4066271 | 0.89 | SLC6A5 (0.38) | HPGDALDH1A1SLC6A5 | |
| SCHEMBL2976410 | 0.88 | HPGD (0.45) | MCHR1KCNH2KDRHRH3HPGD | |
| SCHEMBL2962847 | 0.88 | HPGD (0.47) | MCHR1KCNH2KDRHRH3HPGD | |
| SCHEMBL4064790 | 0.86 | MRGPRX4 (0.39) | HPGDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4068787 | 0.86 | MRGPRX4 (0.40) | HPGDALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4072173 | 0.86 | ATM (0.40) | MCHR1HPGDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4069211 | 0.84 | MRGPRX4 (0.41) | HPGDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2973369 | 0.81 | EPHX2 (0.52) | HPGDSCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658289-B1 | 3-SUBSTITUTED IMIDAZOPYRIDINE-DERIVATIVES AS C-KIT INHIBITORS | OSI PHARM INC (US) | 2009-03-18 | — | — | EP | claimed |