Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4069255 | 0.89 | MCHR1 (0.42) | SLC6A5ALDH1A1HPGD | |
| SCHEMBL2971081 | 0.89 | SLC6A5 (0.42) | SLC6A5ALDH1A1MEN1KMT2ADRD3 | |
| SCHEMBL4065692 | 0.89 | KDR (0.43) | ALDH1A1HPGD | |
| SCHEMBL4061393 | 0.87 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL4064790 | 0.85 | MRGPRX4 (0.39) | HPGDPPARDPPARAPPARG | |
| SCHEMBL4068787 | 0.85 | MRGPRX4 (0.40) | ALDH1A1HPGDPPARDPPARAPPARG | |
| SCHEMBL4072173 | 0.85 | ATM (0.40) | SLC6A5ATMHPGDPPARDPPARA | |
| SCHEMBL4069211 | 0.83 | MRGPRX4 (0.41) | HPGDPPARDPPARAPPARG | |
| SCHEMBL1377468 | 0.81 | MEN1 (0.54) | SLC6A5ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4065690 | 0.81 | BRD4 (0.39) | MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658289-B1 | 3-SUBSTITUTED IMIDAZOPYRIDINE-DERIVATIVES AS C-KIT INHIBITORS | OSI PHARM INC (US) | 2009-03-18 | — | — | EP | claimed |